Endocrine Abstracts

Diabetes Mellitus (DM) is, characterized by high blood glucose levels, one of the most common chronic diseases worldwide. In 2021, according to International Diabetes Federation, 537 million adults aged between 20 and 79 are diagnosed with DM. Environmental and genetic factors affect its etiopathogenesis. Disturbances in emotions or emotion regulation are regarded as a major contributor to the pathophysiology and etiology of the disease. People with DM who experience diabetes ...

Background: Acromegaly which is caused by excessive growth hormone is a rare chronicle endocrine disorder. Because it is a rare disorder, limited data are available on the impact and consequences of acromegaly on the mental health of patients, but the investigations are growing over time.Aim: It aims to summarize the evidence identifying the mental health issues of patients with acromegaly.Methods: MEDLINE (PubMed), Web of Science,...

Introduction: Dapagliflozin is sodium-glucose co-transporter receptor 2 (SGLT2) inhibitor that is recently discovered an oral antidiabetic (OAD) agent that improves glycemic control by increasing the renal excretion of glucose. Vulvovaginal candidiasis (VVC) is the infection of the vaginal vestibuler area. We present a case of VVC accompanied by use of dapagliflozin.Case: A-48-year-old woman who had T2DM since 8 years was admitted to the endocrinology cl...

Introduction: Metformin-induced lactic acidosis (MALA) is one of the most important drug toxicities with high morbidity and mortality rates. Nonspecific symptoms such as nausea, vomiting, epigastric pain, hypotension, tachycardia, tachypnea, arrhythmia, renal insufficiency, coma and cardiac arrest can be seen. Here we are presenting a case with acidosis due to metformin overdose.Case: A 36-year-old female patient with a history of type 2 diabetes for thr...

Background: Exercise training has become an important adjunct therapy for both the prevention and management of type II diabetes mellitus. Interest in telemedicine is increasing as a potentially innovative and sustainable intervention approach to diabetes management. Telemedicine can facilitate the achievement of individualized treatment goals by training patients to manage their own disease.Objective: To evaluate the effect of telemedicine on exercise c...

Introduction: High level of Parathormone (PTH) impair bone health by increasing the risk of fracture. The aim is to determine the threshold value of PTH elevation to accompany deficiency or failure of Vit D. This may be an important parameter in assessing bone metabolism in clinical practice.Material and method: 931 patients who were referred to the endocrinology clinic were retrospectively studied and 880 patients diagnosed with Vit D deficiency include...

Anaemia prevalence is reported between 5 and 31.8% in patients with PHPT. Anaemia in PHPT shows correlations with serum calcium, PTH, alkaline phosphatase levels, severity of the bone disease and PHPT duration. In this study we compared pre-operative and post-operative haemogram parameters of patients with PHPT who received a parathyroidectomy at our department. We determined the prevelance of pre-operative anaemia, thrombocytopenia, neutropenia and observed if any of this par...

Introduction: Neutrophil/lymphocyte ratio (NLR) is an indicative of the acute phase response. It is a significant indicator of the systemic inflammation, and considered as a poor prognosis indicator in various disease. We aimed to evaluate NLR and its determinants in acromegaly patients.Patients and methods: A retrospective chart review of 40 patients with acromegaly and 45 age and sex matched healthy individuals was performed. Patients with active infec...

Idiopathic hypoparathyroidism (IHP) is an uncommon disease in which soft tissue calcifications may be seen. We report a case with IHP with asymptomatic hypocalcemia and features of ankylosing spondylitis (AS).Case: A 58-year-old male patient was referred to our department due to incidentally discovered hypocalcemia when admitted with blurred speech, gait and posture abnormalities. He had had a generalized convulsion 19 years ago. On physical examination,...

Background: Worldwide, bread is one of the most consumed foodstuff. White bread is made of white flour and process involves the exclusion of bran and embryo. On contrary, these are preserved in whole wheath. Compared the whole grain bread, most commercial white wheat breads contain little dietary fiber and it is assumed to cause more drastic rise and fall on glucose and insulin levels.Objective: Aiming to investigate 3-hour effect of two different type o...